CGC Bibliography Paper 4964

Epithelial biology: lessons from Caenorhabditis elegans.

Michaux G, Legouis R, Labouesse M

Medline:

11602346

Citation:

Gene 277: 83-100 2001

Type:

REVIEW

Genes:

ajm-1 apr-1 bar-1 che-14 cog-2 dlg-1 elt-1 elt-2 elt-5 elt-6 end-1 end-3 ges-1 glp-1 hmp-1 hpm-2 hmr-1 lag-1 lag-2 let-23 let-413 let-502 let-805 lin-2 lin-7 lin-10 lin-11 lin-12 lin-26 lin-29 lit-1 lrp-1 med-1 med-2 mom-1 mua-3 mup-4 nhr-23 nhr-25 nhr-75 nhr-81 nhr-82 pha-1 pha-4 pop-1 skn-1 sqv-1 sqv-7 sqv-8

Abstract:

Epithelial cells are essential and abundant in all multicellular animals where their dynamic cell shape changes orchestrate morphogenesis of the embryo and individual organs. Genetic analysis in the simple nematode Caenorhabditis elegans provides some clues to the mechanisms isms that are involved in specifying epithelial cell fates and in controlling specific epithelial processes such as junction assembly, trafficking or cell fusion and cell adhesion. Here we review recent findings concerning C elegans epithelial cells, focusing in particular on epithelial polarity, and transcriptional control.