CGC Bibliography Paper 5052

Developmental genetics of spermatogenesis in the nematode Caenorhabditis elegans.

L'Hernault SW, Singson AW

Medline:

Citation:

"The Testis: From Stell Cell to Sperm Function". E Goldberg (ed). Springer-Verlag, New York. : 109-119 2000

Type:

REVIEW

Genes:

spe-4 spe-5 spe-9

Abstract:

In both mammals and C. elegans, spermatogenesis is the process where a spermatogonial cell undergoes a series of divisions to produce a highly differentiated cell, the spermatozoon. Spermatogonial cellular divisions are incomplete in mammals so that all subsequent stages occur in a syncitium. The situation is similar in C. elegans, where spermatogonial nuclei initially share a common cytoplasm. Spermatogonial divisions in both mammals and C. elegans are regulated by signaling from gonadal accessory