CGC Bibliography Paper 5091

AEXpulsing a retrograde signal.

Nonet ML

Medline:

11804562

Citation:

Neuron 33: 155-156 2002

Type:

REVIEW

Genes:

aex-1 eax-5 unc-13

Abstract:

A variety of secreted components have been identified as retrograde signals mediating diverse aspects of synaptic development, maintenance, and plasticity; however, little is known about the mechanisms mediating the release of secreted retrograde signals. Doi and Iwasaki (this issue of Neuron) implicate AEX-1, a protein distantly related to the UNC-13/Munc13 family, as an attractive candidate regulator of the retrograde release machinery in muscle.