Worm Breeder's Gazette 1(2): 19a
These abstracts should not be cited in bibliographies. Material contained herein should be treated as personal communication and should be cited as such only with the consent of the author.
The flu-1 mutants (previously denoted fl-I, M.G.G. 135 39-44) of C. elegans which have a bright autofluorescence of the gut were thought to have much reduced kynurenine hydroxylase activity. The kynurenine hydroxylase activity in the crude extracts of 5 alleles of flu-1 mutant have been measured and found to be less than 7% of the specific activity of N2. This activity cosediments with succinic dehydrogenase activity in equilibrium sucrose density centrifugation. This suggests that kynurenine hydroxylase activity is associated with mitochondria.